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Yeast is one of the premier industrial microorganisms, because of its essential role in brewing, winemaking, baking, and fuel alcohol production. In addition, yeast has proven to be an excellent model organism for the study of a variety of biological problems involving the fields of genetics, molecular biology, cell biology and other disciplines within the biomedical and life sciences.

The complete genomes of the budding yeast (Saccharomyces cerevisiae) and the fission yeast (Schizosaccharomyces pombe) have been determined and those of other yeasts are being sequenced at breath-taking speed. A major focus of current yeast research concerns genome-wide functional analysis-the development of tools and methods to decipher the functions of all the genes of an organism under a variety of environmental conditions. -- On-going groundbreaking work in the functional genomics of the budding and fission yeasts will assure their importance as model eukaryotes in the foreseeable future.

Resources such as yeast strains and DNA clones are absolutely necessary for a wide variety of yeast research. In the past, such resources were stored by individual researchers and were distributed by request. Establishment of a central yeast genetic resource center has been a goal of yeast researchers for many years in order to overcome the inherent inefficiency and inequities of such a system. Thus, the National BioResource Yeast Project was launched in 2002 by the Japanese Ministry of Education, Culture, Sports, Science and Technology.

The purpose of the project is the systematic collection, storage, and dissemination of important yeast genetic resources including strains, plasmids, DNA libraries, and antibodies.

The physical infrastructure of the Yeast Genetic Resource Center (YGRC) is located at Osaka Metropolitan University , Hiroshima Institute of Technology and Hiroshima University to provide the aforementioned services. A Steering Committee has been established to develop operational policies and to assure open communication between the Center and the yeast research community at large.

MIZUNUMA Masaki	Graduate School of Integrated Sciences for Life, Hiroshima University	( Chairperson )
AKADA Rinji	Graduate School of Medicine, Yamaguchi University
AKAO Takeshi	National Research Institute of Brewing
ARAKI Hiroyuki	National Institute of Genetics/ROIS-DS
KAMADA Yoshiaki	National Institute for Basic Biology
KAWAMUKAI Makoto	Faculty of Life and Environmental Science, Shimane University
KITAMURA Kenji	Natural Science Center for Basic Research and Development, Hiroshima University	( Subject Director )
KITAMOTO Hiroko	National Institute for Agro-Environmental Sciences
GOTO Yuhei	National Institute for Basic Biology
SAKUNO Takeshi	Graduate School of Frontier Biosciences, Osaka University
SHINOHARA Miki	Faculty of Agriculture, Kindai University
SUGIYAMA Minetaka	Faculty of Life Sciences, Hiroshima Institute of Technology	( Subject Director )
SUMA Michiko	Okinawa Institute of Science and Technology Graduate University
TAKEGAWA Kaoru	Faculty of Agriculture, Kyushu University
TOHDA Hideki	Chitose Bio Evolution Pte. LTD
NAKAMURA Taro	Graduate School of Science, Osaka Metropolitan University	( Representative )
HARASHIMA Satoshi	Faculty of Biotechnology and Life Science, Sojo University
HIRAOKA Yasushi	Graduate School of Frontier Biosciences, Osaka University
MORIYA Hisao	Research Core for Interdisciplinary Sciences, Okayama University
YAMAGISHI Hiromi	Asahi Breweries, LTD.
YAMASHITA Akira	National Institute for Basic Biology

The two most useful yeast species, Schizosaccharomyces pombe (fission yeast) and Saccharomyces cerevisiae (budding yeast), are managed by research groups at Osaka Metropolitan University and Hiroshima Institute of Technology, respectively. These two groups collaborate closely in order to fulfill the goals of the project.

An overview of the YGRC is illustrated as follows:

If you wish to deposit strains or plasmids, please contact the YGRC by E-mail.

Fission yeast (contactus-yeastshigen.info)
Budding yeast (contactus-yeastshigen.info)

Initially, a Material Transfer Agreement (MTA) will be signed and exchanged, in which you will indicate your preferred terms for future distribution of provided materials. You will then be asked to send the materials and to provide as much background information as possible (i.e., restriction maps, details about mutant isolation or construction, etc.) in order to make the materials a useful resource for future users. In the case of large contributions, the YGRC will send technical personnel to your laboratory to facilitate the transfer of materials.

Strains are stored in glycerol at -80^oC. When new strains are deposited, phenotypes of most are confirmed. Strains harboring new combinations of mutant alleles are also constructed at the YGRC.

Information about most strains and plasmids stored at the YGRC is available online and is searchable based on genotype or other relevant parameters.

If you wish to obtain yeast strains, plasmids or libraries, please contact us by E-mail. After receiving the materials you will be asked to complete, sign, and return to us an appropriate MTA. Depending on the materials, you may need to provide us with an agreement signed in advance by the Intellectual Property Right (IPR) holder.